Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I

Both nuclear factor (NF)-κB–inducing kinase (NIK) and inhibitor of κB (IκB) kinase (IKK) have been implicated as essential components for NF-κB activation in response to many external stimuli. However, the exact roles of NIK and IKKα in cytokine signaling still remain controversial. With the use of...

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Bibliographic Details
Main Authors: Matsushima, Akemi, Kaisho, Tsuneyasu, Rennert, Paul D., Nakano, Hiroyasu, Kurosawa, Kyoko, Uchida, Daisuke, Takeda, Kiyoshi, Akira, Shizuo, Matsumoto, Mitsuru
Format: Online
Language:English
Published: The Rockefeller University Press 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193391/