The Innate Mononuclear Phagocyte Network Depletes B Lymphocytes through Fc Receptor–dependent Mechanisms during Anti-CD20 Antibody Immunotherapy
Anti-CD20 antibody immunotherapy effectively treats non-Hodgkin's lymphoma and autoimmune disease. However, the cellular and molecular pathways for B cell depletion remain undefined because human mechanistic studies are limited. Proposed mechanisms include antibody-, effector cell–, and complem...
Main Authors: | Uchida, Junji, Hamaguchi, Yasuhito, Oliver, Julie A., Ravetch, Jeffrey V., Poe, Jonathan C., Haas, Karen M., Tedder, Thomas F. |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212805/ |
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