The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

The Inositol Polyphosphate 5-Phosphatase Ship Is a Crucial Negative Regulator of B Cell Antigen Receptor Signaling

Ship is an Src homology 2 domain containing inositol polyphosphate 5-phosphatase which has been implicated as an important signaling molecule in hematopoietic cells. In B cells, Ship becomes associated with Fcγ receptor IIB (FcγRIIB), a low affinity receptor for the Fc portion of immunoglobulin (Ig)...

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Bibliographic Details
Main Authors: Liu, Qiurong, Oliveira-Dos-Santos, Antonio J., Mariathasan, Sanjeev, Bouchard, Denis, Jones, Jamie, Sarao, Renu, Kozieradzki, Ivona, Ohashi, Pamela S., Penninger, Josef M., Dumont, Daniel J.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212495/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212495/

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