Vav Regulates Peptide-specific Apoptosis in Thymocytes

Vav Regulates Peptide-specific Apoptosis in Thymocytes

The protooncogene Vav functions as a GDP/GTP exchange factor (GEF) for Rho-like small GTPases involved in cytoskeletal reorganization and cytokine production in T cells. Gene-targeted mice lacking Vav have a severe defect in positive and negative selection of T cell antigen receptor transgenic thymo...

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Bibliographic Details
Main Authors: Kong, Young-Yun, Fischer, Klaus-Dieter, Bachmann, Martin F., Mariathasan, Sanjeev, Kozieradzki, Ivona, Nghiem, Mai P., Bouchard, Dennis, Bernstein, Alan, Ohashi, Pamela S., Penninger, Josef M.
Format: Online
Language:English
Published: The Rockefeller University Press 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212394/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212394/

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