Major Histocompatibility Complex Class II Expression by Intrinsic Renal Cells Is Required for Crescentic Glomerulonephritis
The requirement for major histocompatibility complex class II (MHC II) to initiate immune renal injury was studied in a murine model of CD4+ T cell–dependent crescentic glomerulonephritis (GN). C57BL/6 (MHC II+/+ ) mice developed crescentic GN with glomerular CD4+ T cell infiltration and renal injur...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212465/ |