Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis

The plasminogen/plasmin system has the potential to affect the outcome of inflammatory diseases by regulating accumulation of fibrin and other matrix proteins. In human and experimental crescentic glomerulonephritis (GN), fibrin is an important mediator of glomerular injury and renal impairment. Glo...

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Bibliographic Details
Main Authors: Kitching, A. Richard, Holdsworth, Stephen R., Ploplis, Victoria A., Plow, Edward F., Collen, Désiré, Carmeliet, Peter, Tipping, Peter G.
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196158/