Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8+ T Cells
CD8+ T cells play a central role in the resolution and containment of viral infections. A key effector function of CD8+ T cells is their cytolytic activity toward infected cells. Here, we studied the regulation of cytolytic activity in naive, effector, and central versus effector memory CD8+ T cells...
Main Authors: | Wolint, Petra, Betts, Michael R., Koup, Richard A., Oxenius, Annette |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2004
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211884/ |
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