Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy

One enigma in tumor immunology is why animals bearing malignant grafts can reject normal grafts that express the same nonself-antigen. An explanation for this phenomenon could be that different T cell clones react to the normal graft and the malignant cells, respectively, and only the tumor-reactive...

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Bibliographic Details
Main Authors: Wick, Maresa, Dubey, Purnima, Koeppen, Hartmut, Siegel, Christopher T., Fields, Patrick E., Chen, Lieping, Bluestone, Jeffrey A., Schreiber, Hans
Format: Online
Language:English
Published: The Rockefeller University Press 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198977/