HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development

by Hack, Stephen P., Bruey, Jean-Marie, Koeppen, Hartmut
Published 2014

MET Suppresses Epithelial VEGFR2 via Intracrine VEGF-induced Endoplasmic Reticulum-associated Degradation

by Chen, Tom T., Filvaroff, Ellen, Peng, Jing, Marsters, Scot, Jubb, Adrian, Koeppen, Hartmut, Merchant, Mark, Ashkenazi, Avi
Published 2015

Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy

by Wick, Maresa, Dubey, Purnima, Koeppen, Hartmut, Siegel, Christopher T., Fields, Patrick E., Chen, Lieping, Bluestone, Jeffrey A., Schreiber, Hans
Published 1997

High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate

by Ingle, Gladys S, Chan, Pamela, Elliott, J Michael, Chang, Wesley S, Koeppen, Hartmut, Stephan, Jean-Philippe, Scales, Suzie J
Published 2008

High cell-surface density of HER2 deforms cell membranes

by Chung, Inhee, Reichelt, Mike, Shao, Lily, Akita, Robert W., Koeppen, Hartmut, Rangell, Linda, Schaefer, Gabriele, Mellman, Ira, Sliwkowski, Mark X.
Published 2016

p21-activated kinase 1: PAK'ed with potential

by Ong, Christy C., Jubb, Adrian M., Zhou, Wei, Haverty, Peter M., Harris, Adrian L., Belvin, Marcia, Friedman, Lori S., Koeppen, Hartmut, Hoeflich, Klaus P.
Published 2011

TMEFF2 Is a PDGF-AA Binding Protein with Methylation-Associated Gene Silencing in Multiple Cancer Types Including Glioma

by Lin, Kui, Taylor, James R., Wu, Thomas D., Gutierrez, Johnny, Elliott, J. Michael, Vernes, Jean-Michel, Koeppen, Hartmut, Phillips, Heidi S., de Sauvage, Frederic J., Meng, Y. Gloria
Published 2011

Intratumoral characteristics of tumor and immune cells at baseline and on-treatment correlated with clinical responses to MPDL3280A, an engineered antibody against PD-L1

by Kohrt, Holbrook, Kowanetz, Marcin, Gettinger, Scott, Powderly, John, Koeppen, Hartmut, Sosman, Jeffrey A, Cruz, Cristina, Xiao, Yuanyuan, Mokatrin, Ahmad, Fine, Gregg, Chen, Daniel S, Hodi, F Stephen
Published 2013

MET Gene Copy Number Alterations and Expression of MET and Hepatocyte Growth Factor Are Potential Biomarkers in Angiosarcomas and Undifferentiated Pleomorphic Sarcomas

by Schmitz, Katja, Koeppen, Hartmut, Binot, Elke, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela A., Heydt, Carina, Wardelmann, Eva, Büttner, Reinhard, Merkelbach-Bruse, Sabine, Rüschoff, Josef, Schildhaus, Hans-Ulrich
Published 2015

Targeted Biomarker Profiling of Matched Primary and Metastatic Estrogen Receptor Positive Breast Cancers

by Schleifman, Erica B., Desai, Rupal, Spoerke, Jill M., Xiao, Yuanyuan, Wong, Cheryl, Abbas, Ilma, O’Brien, Carol, Patel, Rajesh, Sumiyoshi, Teiko, Fu, Ling, Tam, Rachel N., Koeppen, Hartmut, Wilson, Timothy R., Raja, Rajiv, Hampton, Garret M., Lackner, Mark R.
Published 2014

Development of a robust RNA-based classifier to accurately determine ER, PR, and HER2 status in breast cancer clinical samples

by Wilson, Timothy R., Xiao, Yuanyuan, Spoerke, Jill M., Fridlyand, Jane, Koeppen, Hartmut, Fuentes, Eloisa, Huw, Ling Y., Abbas, Ilma, Gower, Arjan, Schleifman, Erica B., Desai, Rupal, Fu, Ling, Sumiyoshi, Teiko, O’Shaughnessy, Joyce A., Hampton, Garret M., Lackner, Mark R.
Published 2014

Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma

by Wallin, Jeffrey J., Bendell, Johanna C., Funke, Roel, Sznol, Mario, Korski, Konstanty, Jones, Suzanne, Hernandez, Genevive, Mier, James, He, Xian, Hodi, F. Stephen, Denker, Mitchell, Leveque, Vincent, Cañamero, Marta, Babitski, Galina, Koeppen, Hartmut, Ziai, James, Sharma, Neeraj, Gaire, Fabien, Chen, Daniel S., Waterkamp, Daniel, Hegde, Priti S., McDermott, David F.
Published 2016

Circulating and tumor-based biomarkers predict clinical activity in cancer patients treated with the engineered anti-PD-L1 antibody MPDL3280A

by Kowanetz, Marcin, Rabe, Christina, Xiao, Yuanyuan, Wu, Qun J, Koeppen, Hartmut, Leddy, Cecilia, Patel, Rajesh D, Powderly, John, Kohrt, Holbrook, Gettinger, Scott, Soria, Jean-Charles, Herbst, Roy S, Desai, Rupal, Denker, Mitchell, Ruppel, Jane, Boe, Marigold, Nakamura, Rin, Fu, Ling, Sumiyoshi, Teiko, Mokatrin, Ahmad, Shen, Xiaodong, Fine, Gregg, Chen, Daniel S, Hegde, Priti S
Published 2014

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

by Ong, Christy C, Gierke, Sarah, Pitt, Cameron, Sagolla, Meredith, Cheng, Christine K, Zhou, Wei, Jubb, Adrian M, Strickland, Laura, Schmidt, Maike, Duron, Sergio G, Campbell, David A, Zheng, Wei, Dehdashti, Seameen, Shen, Min, Yang, Nora, Behnke, Mark L, Huang, Wenwei, McKew, John C, Chernoff, Jonathan, Forrest, William F, Haverty, Peter M, Chin, Suet-Feung, Rakha, Emad A, Green, Andrew R, Ellis, Ian O, Caldas, Carlos, O’Brien, Thomas, Friedman, Lori S, Koeppen, Hartmut, Rudolph, Joachim, Hoeflich, Klaus P
Published 2015