Critical Role for Tumor Necrosis Factor–related Apoptosis-inducing Ligand in Immune Surveillance Against Tumor Development

Natural killer (NK) cells and interferon (IFN)-γ have been implicated in immune surveillance against tumor development. Here we show that tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) plays a critical role in the NK cell–mediated and IFN-γ–dependent tumor surveillance. Administrati...

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Bibliographic Details
Main Authors: Takeda, Kazuyoshi, Smyth, Mark J., Cretney, Erika, Hayakawa, Yoshihiro, Kayagaki, Nobuhiko, Yagita, Hideo, Okumura, Ko
Format: Online
Language:English
Published: The Rockefeller University Press 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193611/