Type I Interferons (IFNs) Regulate Tumor Necrosis Factor–related Apoptosis-inducing Ligand (TRAIL) Expression on Human T Cells: A Novel Mechanism for the Antitumor Effects of  Type I IFNs

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a proapoptotic member of the TNF family of type II membrane proteins, which constitutes one component of T cell cytotoxicity. In this study, we investigated the expression and function of TRAIL in human peripheral blood T (PBT)...

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Bibliographic Details
Main Authors: Kayagaki, Nobuhiko, Yamaguchi, Noriko, Nakayama, Masafumi, Eto, Hiroshi, Okumura, Ko, Yagita, Hideo
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193058/