Grf40, A Novel Grb2 Family Member, Is Involved in T Cell Signaling through Interaction with SLP-76 and LAT

Grf40, A Novel Grb2 Family Member, Is Involved in T Cell Signaling through Interaction with SLP-76 and LAT

We molecularly cloned a new Grb2 family member, named Grf40, containing the common SH3-SH2-SH3 motif. Expression of Grf40 is predominant in hematopoietic cells, particularly T cells. Grf40 binds to the SH2 domain–containing leukocyte protein of 76 kD (SLP-76) via its SH3 domain more tightly than Grb...

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Bibliographic Details
Main Authors: Asada, Hiroshi, Ishii, Naoto, Sasaki, Yoshiteru, Endo, Kazuhiro, Kasai, Hirotake, Tanaka, Nobuyuki, Takeshita, Toshikazu, Tsuchiya, Shigeru, Konno, Tasuke, Sugamura, Kazuo
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193052/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193052/

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