Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

The Src-family and Syk/ZAP-70 family of protein tyrosine kinases (PTK) are required for T cell receptor (TCR) functions. We provide evidence that the Src-family PTK Lck is responsible for regulating the constitutive tyrosine phosphorylation of the TCR zeta subunit in murine thymocytes. Moreover, lig...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1996
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192313/