Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta
Tolerance of monocytes/macrophages to endotoxin (lipopolysaccharide [LPS]) can be induced both in vivo and in vitro by LPS itself. Exposure to LPS, even at a very low dose, induces a downregulation of cytokine response to a second high dose LPS challenge. To learn more about the unknown mechanisms o...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1995
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191997/ |