Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

Activated mouse peritoneal macrophages produce nitric oxide (NO) via a nitric oxide synthase that is inducible by interferon gamma (IFN- gamma): iNOS. We have studied the mechanisms by which transforming growth factor beta 1 (TGF-beta) suppresses IFN-gamma-stimulated NO production. TGF-beta treatmen...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1993
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191129/