Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice

Intercellular adhesion molecule 1 (ICAM-1) is one of three immunoglobulin superfamily members that bind to the integrins lymphocyte function associated 1 (LFA-1) and Mac-1 on leukocytes. We have generated mice that are genetically and functionally deficient in ICAM-1. These mice have elevated number...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1994
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191562/