P-Selectin or Intercellular Adhesion Molecule (Icam)-1 Deficiency Substantially Protects against Atherosclerosis in Apolipoprotein E–Deficient Mice

The expression of leukocyte and endothelial cell adhesion molecules (CAMs) is essential for the emigration of leukocytes during an inflammatory response. The importance of the inflammatory response in the development of atherosclerosis is indicated by the increased expression of adhesion molecules,...

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Bibliographic Details
Main Authors: Collins, Robert G., Velji, Rizwan, Guevara, Natalia V., Hicks, M. John, Chan, Lawrence, Beaudet, Arthur L.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2195808/