Numb Is an Endocytic Protein

Numb is a protein that in Drosophila determines cell fate as a result of its asymmetric partitioning at mitosis. The function of Numb has been linked to its ability to bind and to biologically antagonize Notch, a membrane receptor that also specifies cell fate. The biochemical mechanisms underlying...

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Bibliographic Details
Main Authors: Santolini, Elisa, Puri, Claudia, Salcini, Anna Elisabetta, Gagliani, Maria Cristina, Pelicci, Pier Giuseppe, Tacchetti, Carlo, Di Fiore, Pier Paolo
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190585/