Tyrosine Phosphorylation of Eps15 Is Required for Ligand-Regulated, but Not Constitutive, Endocytosis

Membrane receptors are internalized either constitutively or upon ligand engagement. Whereas there is evidence for differential regulation of the two processes, little is known about the molecular machinery involved. Previous studies have shown that an unidentified kinase substrate is required for e...

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Bibliographic Details
Main Authors: Confalonieri, Stefano, Salcini, Anna Elisabetta, Puri, Claudia, Tacchetti, Carlo, Di Fiore, Pier Paolo
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175269/