Experimental IgA nephropathy

An animal model for IgA immune complex nephritis was developed. IgA immune complexes formed in vitro with an IgA anti-dinitrophenyl (DNP) derived from MOPC-315 plasmacytoma, and dinitrophenylated bovine serum albumin (DNP-BSA) produced mild focal glomerulonephritis in mice. Similar, but more severe...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1979
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185701/