Regulation of autoimmunity and donor cell engraftment by recipient Lyt- 2+ cells during the graft-versus-host reaction
When lymphocytes from DBA/2 mice are transferred to (C57BL X DBA/2)F1 (BDF1) mice, the ensuing graft-vs.-host reaction (GVHR) causes an autoimmune illness resembling human SLE. To examine the role of recipient T cells in this process, BDF1 mice were depleted of L3T4+ or Lyt-2+ cells by thymectomy fo...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1987
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2188701/ |