Mutant monoclonal antibodies with alterations in biological functions
Somatic cell mutants with deletions in the immunoglobulin constant region were isolated from an IgG(2b) Ar-binding hybridoma. Rat anti-mouse immunoglobulins were used to identify the sites of the deletions. The mutant monoclonal antibodies differ from the parental molecule in their assembly states a...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1982
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186830/ |