Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice
In young adulthood, MRL/Mp-lpr/lpr mice develop severe systemic lupus erythematosus (SLE)-like syndrome associated with massive T cell proliferation. The congenic MRL/Mp- mice lack the lpr gene and develop chronic SLE late in life. We have exchanged thymic transplants between these substrains so as...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1981
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186176/ |