Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
Nitric oxide (.NO) may exhibit proinflammatory features. .NO synthase type 2 (NOS2) is overexpressed and .NO overproduced in rodent models of induced inflammation. Blockage of .NO production by administration of NOS inhibitors prevents or reduces various types of induced inflammation in mice and rat...
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| Format: | Online |
| Language: | English |
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1998
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533351/ |