Regulation of specific cell-mediated cytotoxic response against SV40- induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice

When cyclophosphamide was administered to mice before immunization with syngeneic SV40 transformed cells, the specific immune response elicited, as was measured by in vitro 51Cr release assay was stronger and lasted longer when compared to the response generated in noncyclophosphamide-treated mice....

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1979
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2184834/