B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus- dependent and independent forms of the same hapten

Neonatal splenic B cells which are responsive to thymus-dependent antigens (TD) are exquisitely susceptible to induction of tolerance (1,2). This state of tolerance is not mediated by suppressor T cells and is not a result of suboptimal macrophage function (1 and footnote one). In adult mice, induct...

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Bibliographic Details
Main Authors: Cambier, JC, Vitetta, ES, Uhr, JW, Kettman
Format: Online
Language:English
Published: The Rockefeller University Press 1977
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180712/