B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus- dependent and independent forms of the same hapten
Neonatal splenic B cells which are responsive to thymus-dependent antigens (TD) are exquisitely susceptible to induction of tolerance (1,2). This state of tolerance is not mediated by suppressor T cells and is not a result of suboptimal macrophage function (1 and footnote one). In adult mice, induct...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
1977
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180712/ |