53BP1 is required for class switch recombination

53BP1 participates early in the DNA damage response and is involved in cell cycle checkpoint control. Moreover, the phenotype of mice and cells deficient in 53BP1 suggests a defect in DNA repair (Ward et al., 2003b). Therefore, we asked whether or not 53BP1 would be required for the efficient repair...

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Bibliographic Details
Main Authors: Ward, Irene M., Reina-San-Martin, Bernardo, Olaru, Alexandru, Minn, Kay, Tamada, Koji, Lau, Julie S., Cascalho, Marilia, Chen, Lieping, Nussenzweig, Andre, Livak, Ferenc, Nussenzweig, Michel C., Chen, Junjie
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172356/