βIVΣ1 spectrin stabilizes the nodes of Ranvier and axon initial segments

βIVΣ1 spectrin stabilizes the nodes of Ranvier and axon initial segments

Saltatory electric conduction requires clustered voltage-gated sodium channels (VGSCs) at axon initial segments (AIS) and nodes of Ranvier (NR). A dense membrane undercoat is present at these sites, which is thought to be key for the focal accumulation of channels. Here, we prove that βIVΣ1 spectrin...

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Bibliographic Details
Main Authors: Lacas-Gervais, Sandra, Guo, Jun, Strenzke, Nicola, Scarfone, Eric, Kolpe, Melanie, Jahkel, Monika, De Camilli, Pietro, Moser, Tobias, Rasband, Matthew N., Solimena, Michele
Format: Online
Language:English
Published: The Rockefeller University Press 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172023/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172023/

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