A HIERARCHY OF ANKYRIN/SPECTRIN COMPLEXES CLUSTERS SODIUM CHANNELS AT NODES OF RANVIER

The scaffolding protein ankyrinG is required for Na+ channel clustering at axon initial segments. It is also considered essential for Na+ channel clustering at nodes of Ranvier to facilitate fast and efficient action potential propagation. However, in contrast to these widely accepted roles, we show...

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Bibliographic Details
Main Authors: Ho, Tammy Szu-Yu, Zollinger, Daniel R., Chang, Kae-Jiun, Xu, Mingxuan, Cooper, Edward C., Stankewich, Michael C., Bennett, Vann, Rasband, Matthew N.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271271/