CDK4 regulation by TNFR1 and JNK is required for NF-κB–mediated epidermal growth control

Nuclear factor κB (NF-κB) mediates homeostatic growth inhibition in the epidermis, and a loss of NF-κB function promotes proliferation and oncogenesis. To identify mechanisms responsible for these effects, we impaired NF-κB action in the epidermis by three different genetic approaches, including con...

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Bibliographic Details
Main Authors: Zhang, Jennifer Y., Tao, Shiying, Kimmel, Robin, Khavari, Paul A.
Format: Online
Language:English
Published: The Rockefeller University Press 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171750/