Molecular Determinants of PI(4,5)P2 and PI(3,4,5)P3 Regulation of the Epithelial Na+ Channel

Molecular Determinants of PI(4,5)P2 and PI(3,4,5)P3 Regulation of the Epithelial Na+ Channel

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) are physiologically important second messengers. These molecules bind effector proteins to modulate activity. Several types of ion channels, including the epithelial Na+ channel (ENaC), are p...

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Bibliographic Details
Main Authors: Pochynyuk, Oleh, Tong, Qiusheng, Medina, Jorge, Vandewalle, Alain, Staruschenko, Alexander, Bugaj, Vladislav, Stockand, James D.
Format: Online
Language:English
Published: The Rockefeller University Press 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151653/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151653/

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