Restructuring of Focal Adhesion Plaques by Pi 3-Kinase: Regulation by Ptdins (3,4,5-P)3 Binding to α-Actinin
Focal adhesions are an elaborate network of interconnecting proteins linking actin stress fibers to the extracellular matrix substrate. Modulation of the focal adhesion plaque provides a mechanism for the regulation of cellular adhesive strength. Using interference reflection microscopy, we found th...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2000
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175186/ |