Restructuring of Focal Adhesion Plaques by Pi 3-Kinase: Regulation by Ptdins (3,4,5-P)3 Binding to α-Actinin

Focal adhesions are an elaborate network of interconnecting proteins linking actin stress fibers to the extracellular matrix substrate. Modulation of the focal adhesion plaque provides a mechanism for the regulation of cellular adhesive strength. Using interference reflection microscopy, we found th...

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Bibliographic Details
Main Authors: Greenwood, Jeffrey A., Theibert, Anne B., Prestwich, Glenn D., Murphy-Ullrich, Joanne E.
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175186/