Dynamic Inositol Trisphosphate-mediated Calcium Signals within Astrocytic Endfeet Underlie Vasodilation of Cerebral Arterioles

Active neurons communicate to intracerebral arterioles in part through an elevation of cytosolic Ca2+ concentration ([Ca2+]i) in astrocytes, leading to the generation of vasoactive signals involved in neurovascular coupling. In particular, [Ca2+]i increases in astrocytic processes (“endfeet”), which...

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Bibliographic Details
Main Authors: Straub, Stephen V., Bonev, Adrian D., Wilkerson, M. Keith, Nelson, Mark T.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151598/