Influence of exogenous RAR alpha gene on MDR1 expression and P-glycoprotein function in human and rodent cell lines.

The goal of our study was to obtain direct evidence of co-ordinated regulation of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) and differentiation in tumour cells and to study some signalling pathways involved in joint regulation of these two cell phenotypes. The sublines of human melan...

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Bibliographic Details
Main Authors: Stromskaya, T. P., Rybalkina, E. Y., Shtil, A. A., Zabotina, T. N., Filippova, N. A., Stavrovskaya, A. A.
Format: Online
Language:English
Published: Nature Publishing Group 1998
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150321/