THE STRUCTURAL BASIS FOR BINDING OF COMPLEMENT BY IMMUNOGLOBULIN M

An insight into the structural features of human IgM that are responsible for its capacity to bind the first component of complement (C) has been obtained by examining the ability of IgM subfragments to bind active C1 (C1). The smallest two fragments found to bind C1 were the major CNBr fragment of...

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Bibliographic Details
Main Authors: Hurst, Mary M., Volanakis, John E., Hester, Raymond B., Stroud, Robert M., Bennett, J. Claude
Format: Online
Language:English
Published: The Rockefeller University Press 1974
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139640/