INCOMPLETE SIMIAN PAPOVAVIRUS SV40 : FORMATION OF NON-INFECTIOUS VIRAL ANTIGEN IN THE PRESENCE OF FLUOROURACIL

A study was made of the effects of 5-fluorouracil (FU) and 5-fluorodeoxyuridine (FUDR) on the replication of the simian papovavirus SV40 in cercopithecus monkey kidney cells and on the production of virus antigen by these cells. Both drugs markedly suppressed the production of new infectious virus...

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Bibliographic Details
Main Authors: Melnick, Joseph L., Stinebaugh, Sara E., Rapp, Fred
Format: Online
Language:English
Published: The Rockefeller University Press 1964
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137840/