Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

Deregulation of ErbB signaling plays a key role in the progression of multiple human cancers. To help understand ErbB signaling quantitatively, in this work we combine traditional experiments with computational modeling, building a model that describes how stimulation of all four ErbB receptors with...

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Bibliographic Details
Main Authors: Birtwistle, Marc R, Hatakeyama, Mariko, Yumoto, Noriko, Ogunnaike, Babatunde A, Hoek, Jan B, Kholodenko, Boris N
Format: Online
Language:English
Published: Nature Publishing Group 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132449/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132449/

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