IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM.
The experiments here described indicate that the peptone fractions can alter the different blood elements in such a manner as to affect their immunological reactions. This power is not possessed by all the peptones equally, either qualitatively or quantitatively. If we regard the phenomenon of hemo...
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| Format: | Online |
| Language: | English |
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The Rockefeller University Press
1912
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124947/ |
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pubmed-2124947 |
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oai_dc |
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pubmed-21249472008-04-18 IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. Epstein, Albert A. Article The experiments here described indicate that the peptone fractions can alter the different blood elements in such a manner as to affect their immunological reactions. This power is not possessed by all the peptones equally, either qualitatively or quantitatively. If we regard the phenomenon of hemolysis by immune serum in the light of a biochemical process, depending upon properties inherent in certain constituents of the serum and the red blood cells, the experiments described reveal a number of facts concerning the immunochemical action of albumoses and peptones. These substances, which depend for their separation and identification upon purely physical means, show differences in their behavior toward the elements concerned in the production of hemolysis. Inagaki (7) has shown that the albumoses can combine with nucleohiston. It is not improbable, therefore, that some of the reactions are chemical as well as physicochemical in character. Further studies are necessary to determine whether the reactions elicited can aid us in the differentiation of the peptone bodies, for which at present we possess but few tests. The results, however, are suggestive, and may aid in recognizing the presence of these substances in blood serum. The Rockefeller University Press 1912-05-01 /pmc/articles/PMC2124947/ /pubmed/19867542 Text en Copyright © Copyright, 1912, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Epstein, Albert A. |
| spellingShingle |
Epstein, Albert A. IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| author_facet |
Epstein, Albert A. |
| author_sort |
Epstein, Albert A. |
| title |
IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| title_short |
IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| title_full |
IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| title_fullStr |
IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| title_full_unstemmed |
IMMUNOCHEMICAL STUDIES WITH PEPTONES : I. GENERAL STUDIES WITH PEPTONES AND THE IMMUNE HEMOLYTIC SYSTEM. |
| title_sort |
immunochemical studies with peptones : i. general studies with peptones and the immune hemolytic system. |
| description |
The experiments here described indicate that the peptone fractions can alter the different blood elements in such a manner as to affect their immunological reactions. This power is not possessed by all the peptones equally, either qualitatively or quantitatively. If we regard the phenomenon of hemolysis by immune serum in the light of a biochemical process, depending upon properties inherent in certain constituents of the serum and the red blood cells, the experiments described reveal a number of facts concerning the immunochemical action of albumoses and peptones. These substances, which depend for their separation and identification upon purely physical means, show differences in their behavior toward the elements concerned in the production of hemolysis. Inagaki (7) has shown that the albumoses can combine with nucleohiston. It is not improbable, therefore, that some of the reactions are chemical as well as physicochemical in character. Further studies are necessary to determine whether the reactions elicited can aid us in the differentiation of the peptone bodies, for which at present we possess but few tests. The results, however, are suggestive, and may aid in recognizing the presence of these substances in blood serum. |
| publisher |
The Rockefeller University Press |
| publishDate |
1912 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2124947/ |
| _version_ |
1611416658787696640 |