Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism
In an effort to identify cis-acting elements required for targeting of the somatic hypermutation process in mice, we examined whether a T cell receptor (TCR) transgene under the control of the immunoglobulin (Ig) heavy (H) chain intron enhancer would be mutated in antigen-stimulated B cells. Hybrido...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119303/ |