Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
Ataxia-telangiectasia mutated (ATM)–deficient lymphocytes exhibit defects in coding joint formation during V(D)J recombination in vitro. Similar defects in vivo should affect both T and B cell development, yet the lymphoid phenotypes of ATM deficiency are more pronounced in the T cell compartment. I...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118620/ |