Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after FcγRII-mediated uptake

Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after FcγRII-mediated uptake

Plasmacytoid dendritic cells (pDCs) contribute to innate antiviral immune responses by producing type I interferons. Although human pDCs can induce T cell responses upon viral infection, it remains unclear if pDCs can present exogenous antigens. Here, we show that human pDCs exploit FcγRII (CD32) to...

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Bibliographic Details
Main Authors: Benitez-Ribas, Daniel, Adema, Gosse J., Winkels, Gregor, Klasen, Ina S., Punt, Cornelis J.A., Figdor, Carl G., de Vries, I. Jolanda M.
Format: Online
Language:English
Published: The Rockefeller University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118356/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118356/

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