The glycosyl phosphatidylinositol-linked FcγRIII(PMN) mediates transmembrane signaling events distinct from FcγRII

To investigate the ability of FcγRIII(PMN), the GPI-anchored isoform of FcγRIII (CD16) in polymorphonuclear leukocytes (PMN), to mediate transmembrane signaling events, we measured changes in membrane potential with DiOC(5) and in intracellular calcium with indo-1. FcγR were ligated by anti-FcγRIII...

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Bibliographic Details
Main Authors: Kimberly, RP, Ahlstrom, JW, Click, ME, Edberg, JC
Format: Online
Language:English
Published: The Rockefeller University Press 1990
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187837/