High affinity germinal center B cells are actively selected into the plasma cell compartment
A hallmark of T cell–dependent immune responses is the progressive increase in the ability of serum antibodies to bind antigen and provide immune protection. Affinity maturation of the antibody response is thought to be connected with the preferential survival of germinal centre (GC) B cells that ha...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2006
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118125/ |