Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors
Nerve growth factor (NGF) regulates the microtubule-dependent extension and maintenance of axons by some peripheral neurons. We show here that one effect of NGF is to promote microtubule assembly during neurite outgrowth in PC12 cells. Though NGF causes an increase in total tubulin levels, the forma...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1985
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113947/ |