Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells
The cyclic undecapeptide cyclosporine A (CsA) is a potent immunosuppressive agent that inhibits the initial activation of T lymphocytes. This agent appears to be most effective in blocking the action of mitogens such as concanavalin A and the calcium ionophore A23187, which cause an influx of Ca2+,...
| Format: | Online |
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| Language: | English |
| Published: |
The Rockefeller University Press
1986
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113831/ |