Regulation of microtubule composition and stability during nerve growth factor-promoted neurite outgrowth
We have used the nerve growth factor (NGF)-responsive line of PC12 pheochromocytoma cells as a model system to study microtubule specializations associated with neurite outgrowth. PC12 cells treated with NGF cease proliferating and extend neurites. Long-term NGF treatment results in a two- to threef...
Format: | Online |
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Language: | English |
Published: |
The Rockefeller University Press
1986
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2113813/ |