Inhibition of synthesis of alpha-fetoprotein by glucocorticoids in cultured hepatoma cells

alpha-Fetoprotein (AFP) synthesis was studied in the presence and absence of glucocorticoids in rat hepatoma Mc-A-RH-7777 cells. Radioimmunoassay of media from cell cultures grown in the presence of glucocorticoid (dexamethasone or cortisol) showed a reduction in AFP, an increase in albumin, and no...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1982
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2112836/