MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover
Mitotic centromere-associated kinesin (MCAK)/Kif2C is the most potent microtubule (MT)-destabilizing enzyme identified thus far. However, MCAK's function at the centromere has remained mechanistically elusive because of interference from cytoplasmic MCAK's global regulation of MT dynamics....
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2007
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099197/ |