Displacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splitting

The ring-shaped cohesin complex links sister chromatids until their timely segregation during mitosis. Cohesin is enriched at centromeres where it provides the cohesive counterforce to bipolar tension produced by the mitotic spindle. As a consequence of spindle tension, centromeric sequences transie...

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Bibliographic Details
Main Authors: Ocampo-Hafalla, Maria T., Katou, Yuki, Shirahige, Katsuhiko, Uhlmann, Frank
Format: Online
Language:English
Published: Springer-Verlag 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075529/