P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo.
We examined whether the increased expression of P-glycoprotein (P-gp) encoded by the human multidrug resistance gene MDR1 is related to the acquired multidrug resistance of lung cancer in vivo. We estimated the chemosensitivity of lung cancer xenografts (LC-6, adenocarcinoma; Lu-24, small-cell cance...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
1996
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074809/ |